So I decided to do 2-up, meaning for each paper section I used two pieces of paper, one inside the other. I chose 2 because it was a thicker stock, thinner papers can handle 3. Here is my technique for folding.

Lineup the edges

Push down the middle and then move out.

Give the fold a rub down with your bonefolder or maybe the back of a spoon or something if you don't have one. (Another good substitute is the tip of a potato peeler)

Start organising your folded paper into sections

Your little pile will slowly build up; I find this good motivation. This is the first sign of a book, you can start to feel how much it will weigh and how it feels in your hands

Finally I press the paper for a little while under a weight, this is optional but I find it gives good results. Onto Sewing!